Chemoreduction for Unilateral Retinoblastoma
نویسندگان
چکیده
منابع مشابه
Chemoreduction for unilateral retinoblastoma.
OBJECTIVE To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment. DESIGN Prospective nonrandomized single-center clinical trial. SETTING Ocular Oncology Service at Wills Eye Hospital of Thomas Jefferson University, Philadelphia, Pa, in conjunction with the Division of Oncology at The Children's Hospital of Philadelphia. PARTICIPANTS Thirt...
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OBJECTIVE To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral retinoblastoma). DESIGN Retrospective consecutive case series. PARTICIPANTS Two hundred fourteen consecutive children with newly diagnosed retinoblastoma treated at a major ocular oncology center from January 1, 19...
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BACKGROUND Primary chemotherapy is a new treatment approach in retinoblastoma, aiming to avoid radiogenic adverse effects, such as second tumor-associated mortality, as observed following external beam irradiation. OBJECTIVE To describe the clinical and histopathologic regression pattern after primary chemotherapy in retinoblastoma. METHODS Five patients with sporadic bilateral retinoblasto...
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OBJECTIVE To evaluate the change in regression pattern following chemoreduction and tumor consolidation therapy (thermotherapy or cryotherapy) for retinoblastoma METHODS Retrospective medical record analysis was completed for 557 retinoblastomas (239 eyes of 157 patients) that were treated with chemoreduction and showed regression to 1 of 5 patterns (type 0, no visible remnant; type 1, comple...
متن کاملLong-term visual outcome following chemoreduction for retinoblastoma.
OBJECTIVE To evaluate long-term visual outcome following chemoreduction. DESIGN Interventional case series evaluating 54 eyes of 40 children with retinoblastoma successfully treated with chemoreduction, consisting of a combination of intravenous carboplatin, etoposide phosphate, and vincristine sulfate plus focal therapy without external beam radiotherapy or enucleation. All patients were fol...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2002
ISSN: 0003-9950
DOI: 10.1001/archopht.120.12.1653